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"https://example.org/physiosim/anatomical-contents#heart/mitral_valve", "target_c5": { "applied": false, "provenance": "docs/decisions.md:27", "relation": "part_of", "status": "USER_DECISION_RUNTIME_DEFERRED" } }, "organ": { "crosswalk_review": "PROPOSED", "equivalence": "NONE", "m1_relation": null, "numeric_use": "NONE", "source_context": null, "source_id": "UBERON:0000948", "source_iri": "http://purl.obolibrary.org/obo/UBERON_0000948", "source_provenance": { "full_file_sha256": "288cadbe573f8a5488abc135560a66a3c793f48e32984228a7a791cbdcce24da", "path": "experiments/medmlx_anatomy_mapping/results/contents_catalog.json", "pointer": "#/0" }, "source_relation": { "direction": [ "https://example.org/physiosim/anatomical-contents#heart/organ", null ], "iri": null }, "source_template": "https://example.org/physiosim/anatomical-contents#heart/organ", "target_c5": { "applied": false, "provenance": "docs/decisions.md:27", "relation": "part_of", "status": "USER_DECISION_RUNTIME_DEFERRED" } } }, "dependencies": [ { "dependent": "activation", "kind": "constitutive", "on": [ "heart_rate", "systolic_fraction" ] }, { "dependent": "E_lv(t)", "kind": "constitutive", "on": [ "emin_lv", "emax_lv", "activation" ] }, { "dependent": "P_lv", "kind": "constitutive", "on": [ "E_lv(t)", "V_lv", "V0_lv" ] }, { "dependent": "P_la", "kind": "constitutive", "on": [ "elastance_la", "V_la", "V0_la" ] }, { "dependent": "Q_mitral", "kind": "constitutive", "on": [ "P_la", "P_lv", "resistance_mitral" ] }, { "dependent": "Q_cum_mitral", "kind": "definition", "on": [ "Q_mitral" ] }, { "coefficient": -1, "dependent": "V_la", "kind": "conservation", "on": [ "Q_mitral" ], "scope": "Mitral contribution only; remaining M1 inflows/outflows are unchanged." }, { "coefficient": 1, "dependent": "V_lv", "kind": "conservation", "on": [ "Q_mitral" ], "scope": "Mitral contribution only; remaining M1 inflows/outflows are unchanged." } ], "evidence": { "extracted_facts": "14 knowledge templates, 12 directed relation claims, 2 special reviews and 2 draft boundaries; shared blood concept ID has distinct LA/LV contextual templates.", "interpretations": "Crosswalk roles, constitutive dependencies and M1 scope are explicit project design assertions. No identity, value equivalence or numeric binding is asserted.", "unresolved_conflicts": [ "C5 part_of adapter remains deferred; source located_in and M1 blood_contained_in remain separate.", "LV/LA wall versus myocardium mechanical bearer is unselected.", "Mitral orifice boundary REVIEW; annulus relation REVIEW and definition REVISE; interface DRAFT.", "M1 no-reverse-flow diode restricts signed source transport; no EOA or geometry is represented.", "v2 la_cavity Smith lumped-venous role differs from separate M1 LA state; no identity asserted.", "Inherited M1 batch-TDD review limitation remains unresolved; baseline snapshot is UNREVIEWED." ], "verbatim_evidence": "source.catalog/claims/special_claims/boundaries/sources retain original JSON fields and per-record path/pointer/full-file hash. These are untrusted reference evidence, not adopted axioms." }, "laws": { "E_lv(t)": { "aggregation": "instantaneous law evaluation", "anchor": "E_v(t) = Emin_v + (Emax_v-Emin_v)*a(phi), v in {lv,rv}", "declared_contract": "four_chamber_m1@1.0.0:la-mitral-lv-laws-v1", "inputs": [ "emin_lv", "emax_lv", "activation" ], "integrity_scope": "Declared M1 law/version contract only; does not prove numerical implementation integrity. Observed runtime file hashes are separate provenance.", "kind": "constitutive_law", "line": 63, "path": "docs/physiology_four_chamber_m1.md", "reference": "not applicable", "scope": "Existing M1 equation reference restricted to LA/LV/mitral; not an adopted ontology axiom.", "section": "#equations-and-contract", "sign": "positive elastance", "temporal": "instantaneous", "unit": "mmHg/mL" }, "P_la": { "aggregation": "instantaneous law evaluation", "anchor": "P_a = E_a*(V_a-V0_a), a in {la,ra}, constant positive E_a", "declared_contract": "four_chamber_m1@1.0.0:la-mitral-lv-laws-v1", "inputs": [ "elastance_la", "V_la", "V0_la" ], "integrity_scope": "Declared M1 law/version contract only; does not prove numerical implementation integrity. Observed runtime file hashes are separate provenance.", "kind": "constitutive_law", "line": 65, "path": "docs/physiology_four_chamber_m1.md", "reference": "model gauge pressure relative to one common fixed external pressure of 0 mmHg; no intrathoracic/pericardial pressure", "scope": "Existing M1 equation reference restricted to LA/LV/mitral; not an adopted ontology axiom.", "section": "#equations-and-contract", "sign": "signed common gauge pressure", "temporal": "instantaneous", "unit": "mmHg" }, "P_lv": { "aggregation": "instantaneous law evaluation", "anchor": "P_v = E_v(t)*(V_v-V0_v), v in {lv,rv}", "declared_contract": "four_chamber_m1@1.0.0:la-mitral-lv-laws-v1", "inputs": [ "E_lv(t)", "V_lv", "V0_lv" ], "integrity_scope": "Declared M1 law/version contract only; does not prove numerical implementation integrity. Observed runtime file hashes are separate provenance.", "kind": "constitutive_law", "line": 64, "path": "docs/physiology_four_chamber_m1.md", "reference": "model gauge pressure relative to one common fixed external pressure of 0 mmHg; no intrathoracic/pericardial pressure", "scope": "Existing M1 equation reference restricted to LA/LV/mitral; not an adopted ontology axiom.", "section": "#equations-and-contract", "sign": "signed common gauge pressure", "temporal": "instantaneous", "unit": "mmHg" }, "Q_cum_mitral": { "aggregation": "integral from run start", "anchor": "Cumulative_e(t) = integral from 0 to t of q_e(u) du", "declared_contract": "four_chamber_m1@1.0.0:la-mitral-lv-laws-v1", "inputs": [ "Q_mitral", "time_s" ], "integrity_scope": "Declared M1 law/version contract only; does not prove numerical implementation integrity. Observed runtime file hashes are separate provenance.", "kind": "integral_definition", "line": 70, "path": "docs/physiology_four_chamber_m1.md", "reference": "not applicable", "scope": "Existing M1 equation reference restricted to LA/LV/mitral; not an adopted ontology axiom.", "section": "#equations-and-contract", "sign": "nonnegative LA->LV transport", "temporal": "run_integrated", "unit": "mL" }, "Q_mitral": { "aggregation": "instantaneous law evaluation", "anchor": "q_e = max(dp_e/R_e,0), for the four ideal diodes", "declared_contract": "four_chamber_m1@1.0.0:la-mitral-lv-laws-v1", "inputs": [ "P_la", "P_lv", "resistance_mitral" ], "integrity_scope": "Declared M1 law/version contract only; does not prove numerical implementation integrity. Observed runtime file hashes are separate provenance.", "kind": "constitutive_law", "line": 68, "path": "docs/physiology_four_chamber_m1.md", "reference": "not applicable", "scope": "Existing M1 equation reference restricted to LA/LV/mitral; not an adopted ontology axiom.", "section": "#equations-and-contract", "sign": "nonnegative LA->LV transport", "temporal": "instantaneous", "unit": "mL/s" }, "activation": { "aggregation": "instantaneous law evaluation", "anchor": "a(phi) = (1-cos(2*pi*phi/s))/2, if phi < s; 0 otherwise", "declared_contract": "four_chamber_m1@1.0.0:la-mitral-lv-laws-v1", "implementation": "physiosim.models.cardiovascular.elastance", "inputs": [ "heart_rate", "systolic_fraction" ], "integrity_scope": "Declared M1 law/version contract only; does not prove numerical implementation integrity. Observed runtime file hashes are separate provenance.", "kind": "constitutive_law", "line": 62, "path": "docs/physiology_four_chamber_m1.md", "reference": "not applicable", "scope": "Existing M1 equation reference restricted to LA/LV/mitral; not an adopted ontology axiom.", "section": "#equations-and-contract", "sign": "activation in [0,1]", "temporal": "instantaneous", "unit": "dimensionless" } }, "mitral": { "annulus": { "definition_review": "REVISE", "equivalence": "NONE", "relation_review": "REVIEW", "role": "ANATOMICAL_ATTACHMENT", "template": "mitral_annulus" }, "direction": [ "la", "lv" ], "effective_orifice_area": "NOT_REPRESENTED", "interface": { "equivalence": "NONE", "proposal_id": "boundary-mitral_orifice-transfer-v1", "role": "DRAFT_OPERATIONAL_INTERFACE_CANDIDATE", "signed_flow_allowed": true, "status": "DRAFT_MODEL_CONVENTION" }, "orifice": { "boundary_review": "REVIEW", "equivalence": "NONE", "role": "ANATOMICAL_OPENING", "template": "mitral_orifice" }, "restriction": "M1 ideal diode q=max(dp/R,0) is a restricted no-reverse-flow model relative to the source signed-transport interface; it does not model regurgitation, area or patient geometry.", "valve": { "equivalence": "NONE", "m1_v2_context": { "fma": "FMA:7235", "key": "mitral_valve", "primary_id": "UBERON:0002135", "provenance": "docs/evidence_review/anatomy_nodes_v2.json#/nodes/6", "source_role_in_smith": "location of Q_mt (E29)", "structure": "Mitral valve", "uberon": "UBERON:0002135", "uberon_relation": "same_structure_v2_xref" }, "role": "FLOW_LOCATION_CONTEXT", "template": "mitral_valve" } }, "model_id": "four_chamber_m1", "model_source": { "baseline_snapshot": "456abc8c77134cd8909d603a1d96ed1384bad41f", "declared_contract": "four_chamber_m1@1.0.0:la-mitral-lv-laws-v1", "integrity_scope": "Declared M1 law/version contract only; does not prove numerical implementation integrity. Observed runtime file hashes are separate provenance.", "review": "UNREVIEWED; inherited M1 batch-TDD limitation remains unresolved" }, "model_version": "1.0.0", "parameter_roles": { "elastance_la": { "external_numeric_permission": "NONE", "kind": "parameter", "temporal": "constant_parameter" }, "emax_lv": { "external_numeric_permission": "NONE", "kind": "parameter", "temporal": "constant_parameter" }, "emin_lv": { "external_numeric_permission": "NONE", "kind": "parameter", "temporal": "constant_parameter" }, "heart_rate": { "external_numeric_permission": "NONE", "kind": "parameter", "temporal": "constant_parameter" }, "initial_volumes": { "external_numeric_permission": "NONE", "kind": "parameter", "temporal": "initial" }, "resistance_mitral": { "external_numeric_permission": "NONE", "kind": "parameter", "temporal": "constant_parameter" }, "systolic_fraction": { "external_numeric_permission": "NONE", "kind": "parameter", "temporal": "constant_parameter" }, "unstressed_volumes": { "external_numeric_permission": "NONE", "kind": "parameter", "temporal": "constant_parameter" } }, "parameters": { "elastance_la": { "order": null, "property": "http://bhi.washington.edu/OPB#OPB_00076", "property_source": "https://raw.githubusercontent.com/SemBioProcess/SemGen/master/src/semsim/owl/OPBv1.07.owl", "provenance": "Required explicit caller input; no literature-derived default or calibration.", "temporal": "constant_parameter", "unit": "mmHg/mL" }, "emax_lv": { "order": null, "property": "http://bhi.washington.edu/OPB#OPB_00076", "property_source": "https://raw.githubusercontent.com/SemBioProcess/SemGen/master/src/semsim/owl/OPBv1.07.owl", "provenance": "Required explicit caller input; no literature-derived default or calibration.", "temporal": "constant_parameter", "unit": "mmHg/mL" }, "emin_lv": { "order": null, "property": "http://bhi.washington.edu/OPB#OPB_00076", "property_source": "https://raw.githubusercontent.com/SemBioProcess/SemGen/master/src/semsim/owl/OPBv1.07.owl", "provenance": "Required explicit caller input; no literature-derived default or calibration.", "temporal": "constant_parameter", "unit": "mmHg/mL" }, "heart_rate": { "order": null, "property": "http://bhi.washington.edu/OPB#OPB_01212", "property_source": "https://raw.githubusercontent.com/SemBioProcess/SemGen/master/src/semsim/owl/OPBv1.07.owl", "provenance": "Required explicit caller input; no literature-derived default or calibration.", "temporal": "constant_parameter", "unit": "1/min" }, "initial_volumes": { "order": [ "lv", "sa", "sv", "ra", "rv", "pa", "pv", "la" ], "property": "http://bhi.washington.edu/OPB#OPB_00154", "property_source": "https://raw.githubusercontent.com/SemBioProcess/SemGen/master/src/semsim/owl/OPBv1.07.owl", "provenance": "Required explicit caller input; no literature-derived default or calibration.", "temporal": "initial", "unit": "mL" }, "resistance_mitral": { "order": null, "property": "http://bhi.washington.edu/OPB#OPB_00160", "property_source": "https://raw.githubusercontent.com/SemBioProcess/SemGen/master/src/semsim/owl/OPBv1.07.owl", "provenance": "Required explicit caller input; no literature-derived default or calibration.", "temporal": "constant_parameter", "unit": "mmHg*s/mL" }, "systolic_fraction": { "order": null, "property": "https://example.org/physiosim/concept/systolic_fraction", "property_source": "project-local M1 definition", "provenance": "Required explicit caller input; no literature-derived default or calibration.", "temporal": "constant_parameter", "unit": "dimensionless" }, "unstressed_volumes": { "order": [ "lv", "sa", "sv", "ra", "rv", "pa", "pv", "la" ], "property": "http://bhi.washington.edu/OPB#OPB_00154", "property_source": "https://raw.githubusercontent.com/SemBioProcess/SemGen/master/src/semsim/owl/OPBv1.07.owl", "provenance": "Required explicit caller input; no literature-derived default or calibration.", "temporal": "constant_parameter", "unit": "mL" } }, "ports": { "mitral_flow_port": { "aggregation": "instantaneous", "direction": [ "la", "lv" ], "interpretation": "Flow metadata reference; no duplicate physical state.", "kind": "port", "ref": "Q_mitral", "reference": "not applicable", "sign": "nonnegative LA->LV", "temporal": "instantaneous", "unit": "mL/s" } }, "roles": { "P_la": { "aggregation": "instantaneous", "kind": "algebraic_observable", "sign": "signed common gauge pressure" }, "P_lv": { "aggregation": "instantaneous", "kind": "algebraic_observable", "sign": "signed common gauge pressure" }, "Q_cum_mitral": { "aggregation": "run_integrated", "kind": "auxiliary_integral", "sign": "nonnegative LA->LV transport" }, "Q_mitral": { "aggregation": "instantaneous", "kind": "edge_flow", "sign": "nonnegative LA->LV transport" }, "V_la": { "aggregation": "instantaneous", "kind": "state", "sign": "positive total blood volume" }, "V_lv": { "aggregation": "instantaneous", "kind": "state", "sign": "positive total blood volume" }, "la_pressure_mean_mmhg": { "aggregation": "beat_mean", "kind": "metric", "sign": "manifest-defined metric" }, "lv_edv_sample_ml": { "aggregation": "beat_sample_extremum", "kind": "metric", "sign": "manifest-defined metric" }, "lv_ejection_fraction_sample": { "aggregation": "beat_sample_extremum", "kind": "metric", "sign": "manifest-defined metric" }, "lv_esv_sample_ml": { "aggregation": "beat_sample_extremum", "kind": "metric", "sign": "manifest-defined metric" } }, "sidecar_version": "1.0.0", "source": { "absent_claims": [], "boundaries": { "proposals": [ { "provenance": { "full_file_sha256": "b118f238247486818e16016fd3b17c5bac3e5541477503bbc53ba2ee8ffb82f0", "path": "experiments/medmlx_anatomy_mapping/ontology/boundary_definitions.json", "pointer": "#/proposals/5" }, "record": { "anatomical_base_iri": "http://purl.obolibrary.org/obo/UBERON_0005995", "anatomical_base_label": "mitral valve anulus", "assumptions": [ "A complete hinge locus is identifiable; incomplete or fused/variant configurations require a separately documented variant protocol.", "No arbitrary mm-wide band or tissue thickness is introduced.", "Geometry is not extracted from the existing coarse CT mask." ], "boundary_rule": "Follow the complete 3D leaflet-to-atrioventricular-junction hinge locus through the commissural attachments. Preserve its nonplanarity rather than replacing it with a flat circle.", "bundle": "boundary_valves", "concept_kind": "anatomical_attachment_boundary", "connection_intent": [ "hasAttachmentBoundary", "attachmentBoundaryOf" ], "current_base_iri": "http://purl.obolibrary.org/obo/UBERON_0005995", "definition_basis": "integrated", "definition_status": "DRAFT_MODEL_CONVENTION", "evidence_locator": "\u00a73(a)(i), Fig14", "evidence_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC2440405/" ], "excludes": [ "leaflet free edges and coaptation line", "homogeneous material ring of assumed thickness", "a virtual projected or best-fit annular area", "hemodynamic effective orifice area" ], "functional_rationale": "Use the leaflet attachment locus as the reference supporting the valve apparatus, with closure and opening represented by distinct leaflet states.", "includes": [ "leaflet attachment hinge locus", "commissural attachment landmarks" ], "measurement_performed": false, "model_role": "leaflet-support reference; not itself a blood compartment or resistance parameter", "new_local_predicates": [ "hasAttachmentBoundary", "attachmentBoundaryOf" ], "normative_status": "project operational definition; not new standard ontology equivalence", "observed_geometry": false, "original_mapping_outcome": "REMAINS_REVIEW", "patient_geometry_status": "NOT_MEASURED", "proposal_id": "boundary-mitral_annulus-attachment-v1", "proposal_status": "PROPOSED", "proposal_uri": "https://example.org/physiosim/boundary-proposals#heart/mitral_annulus", "proposed_local_concept": "mitral_leaflet_attachment_boundary", "relation_to_anatomy": "The current UBERON material anulus term remains unchanged. This local boundary is a landmark of attachment tissue, not owl:sameAs or owl:equivalentClass to that tissue. Material support and its boundary are represented separately.", "required_geometry_fields": [ "3D hinge contour in image world mm", "coordinate reference and original image provenance", "cardiac phase or fixation state", "landmark selection method/version", "missing-landmark/variant handling" ], "source_refs": [ "BV01" ], "source_vs_proposal": "Literature motivates the anatomical distinctions; choosing this locus as the project boundary is our proposed modeling convention.", "state_or_phase": "Contour is indexed by cardiac phase t if measured in a living heart; no default systolic/diastolic coordinates are assigned. In fixed specimens record fixation state.", "target_key": "heart/mitral_annulus", "target_template": "https://example.org/physiosim/anatomical-contents#heart/mitral_annulus", "target_uri": "https://example.org/physiosim/anatomical-contents#heart/mitral_annulus", "topological_dimension": 1 } }, { "provenance": { "full_file_sha256": "b118f238247486818e16016fd3b17c5bac3e5541477503bbc53ba2ee8ffb82f0", "path": "experiments/medmlx_anatomy_mapping/ontology/boundary_definitions.json", "pointer": "#/proposals/6" }, "record": { "anatomical_base_iri": "http://purl.org/sig/ont/fma/fma9335", "anatomical_base_label": "Orifice of left atrioventricular junction", "assumptions": [ "The upstream/downstream control-volume partition is declared consistently and avoids overlap/gaps in a future mesh.", "No patient-specific interface geometry, flow, effective area or pressure is inferred from the present CT.", "If landmarks or the required surface construction are absent, this proposal remains symbolic and cannot yield a numerical area.", "A nonplanar hinge contour has infinitely many spanning surfaces; the future construction method is part of the definition, not an anatomical fact." ], "boundary_rule": "Choose an oriented spanning control surface whose boundary is the full nonplanar atrioventricular hinge contour. A surface-construction algorithm and version must be supplied before geometry is instantiated because a contour does not determine a unique spanning surface. Preserve the 3D contour; a planar projection is a different derived representation.", "bundle": "boundary_valves", "competence_assumption": "Only a declared normally competent closed-valve approximation may set cross-interface flow to zero; a closed-phase label alone does not exclude regurgitation or leakage.", "concept_kind": "functional_transfer_interface", "connection_intent": [ "operationallyAssociatedWith", "separatesControlVolumes", "hasBoundaryConstructionRule" ], "current_base_iri": "http://purl.org/sig/ont/fma/fma9335", "definition_basis": "integrated", "definition_status": "DRAFT_MODEL_CONVENTION", "downstream_compartment": "LV", "evidence_locator": "\u00a73(a)(i), Fig14", "evidence_urls": [ "https://pmc.ncbi.nlm.nih.gov/articles/PMC2440405/" ], "excludes": [ "blood material volume", "leaflet tissue or attachment tissue", "leaflet free-edge geometric aperture", "effective orifice area or vena-contracta cross-section", "automatic equality to pressure-separating leaflet surface" ], "functional_rationale": "Define the port across which net volume is transferred between LA and LV; orient the normal in the reference antegrade direction LA \u2192 LV. Reverse/regurgitant transfer is allowed to have negative signed flux.", "includes": [ "a zero-thickness control interface", "a declared boundary-construction rule", "state-dependent reference orientation and signed transport" ], "measurement_performed": false, "model_role": "transport port between declared control volumes; separate from anatomical ostium, actual open gap and functional area property", "new_local_predicates": [ "operationallyAssociatedWith", "separatesControlVolumes", "hasBoundaryConstructionRule" ], "normal_direction": "LA -> LV", "normative_status": "project operational control boundary; not asserted exact mapping to FMA ostium", "observed_geometry": false, "original_mapping_outcome": "REMAINS_REVIEW", "patient_geometry_status": "NOT_MEASURED", "proposal_id": "boundary-mitral_orifice-transfer-v1", "proposal_status": "PROPOSED", "proposal_uri": "https://example.org/physiosim/boundary-proposals#heart/mitral_orifice", "proposed_local_concept": "mitral_transfer_interface", "relation_to_anatomy": "Keep the FMA anatomical opening and its current REVIEW boundary mapping. Link this functional interface with a local operationallyAssociatedWith annotation; do not add owl:sameAs, owl:equivalentClass or unverified standard relation IDs.", "required_geometry_fields": [ "interface mesh or planar region in image world mm", "coordinate reference and original image provenance", "phase/time and surface velocity if moving", "landmark and lumen-boundary provenance", "surface construction algorithm/version", "orientation and mesh integrity checks" ], "source_refs": [ "BV01" ], "source_vs_proposal": "The control-cut choice, flux orientation and required geometry algorithm are project proposals; the sources support anatomical landmarks and the need to distinguish anatomical, geometric and functional definitions.", "state_or_phase": "Phase-specific hinge contour and spanning surface must refer to the same cardiac state. Diastolic opening and systolic closure must not be collapsed into a timeless open area.", "target_key": "heart/mitral_orifice", "target_template": "https://example.org/physiosim/anatomical-contents#heart/mitral_orifice", "target_uri": "https://example.org/physiosim/anatomical-contents#heart/mitral_orifice", "topological_dimension": 2, "transport_definition": "For a moving interface use relative-to-surface velocity when defining net transport Q(t)=integral_S(t) (v-v_surface) dot n dA. This is a proposed measurement definition, not a computed flow result.", "upstream_compartment": "LA" } } ], "status": "DRAFT_MODEL_CONVENTION", "version": "0.1.0" }, "catalog": [ { "provenance": { "full_file_sha256": "288cadbe573f8a5488abc135560a66a3c793f48e32984228a7a791cbdcce24da", "path": "experiments/medmlx_anatomy_mapping/results/contents_catalog.json", "pointer": "#/0" }, "record": { "base_id": "UBERON:0000948", "base_iri": "http://purl.obolibrary.org/obo/UBERON_0000948", "base_label": "heart", "context": null, "key": "organ", "observed_in_CT": false, "profile": "heart", "relation": null, "role": "Structure", "status": "KNOWLEDGE_TEMPLATE_REVIEW", "template_uri": "https://example.org/physiosim/anatomical-contents#heart/organ" } }, { "provenance": { "full_file_sha256": "288cadbe573f8a5488abc135560a66a3c793f48e32984228a7a791cbdcce24da", "path": "experiments/medmlx_anatomy_mapping/results/contents_catalog.json", "pointer": "#/1" }, "record": { "base_id": "UBERON:0002084", "base_iri": "http://purl.obolibrary.org/obo/UBERON_0002084", "base_label": "heart left ventricle", "context": "https://example.org/physiosim/anatomical-contents#heart/organ", "key": "lv", "observed_in_CT": false, "profile": "heart", "relation": "http://purl.obolibrary.org/obo/BFO_0000050", "role": "Structure", "status": "KNOWLEDGE_TEMPLATE_REVIEW", "template_uri": "https://example.org/physiosim/anatomical-contents#heart/lv" } }, { "provenance": { "full_file_sha256": "288cadbe573f8a5488abc135560a66a3c793f48e32984228a7a791cbdcce24da", "path": "experiments/medmlx_anatomy_mapping/results/contents_catalog.json", "pointer": "#/2" }, "record": { "base_id": "UBERON:0016514", "base_iri": "http://purl.obolibrary.org/obo/UBERON_0016514", "base_label": "cavity of left ventricle", "context": "https://example.org/physiosim/anatomical-contents#heart/lv", "key": "lv_cavity", "observed_in_CT": false, "profile": "heart", "relation": "http://purl.obolibrary.org/obo/RO_0002572", "role": "Space", "status": "KNOWLEDGE_TEMPLATE_REVIEW", "template_uri": "https://example.org/physiosim/anatomical-contents#heart/lv_cavity" } }, { "provenance": { "full_file_sha256": "288cadbe573f8a5488abc135560a66a3c793f48e32984228a7a791cbdcce24da", "path": "experiments/medmlx_anatomy_mapping/results/contents_catalog.json", "pointer": "#/3" }, "record": { "base_id": "UBERON:0036285", "base_iri": "http://purl.obolibrary.org/obo/UBERON_0036285", "base_label": "wall of left ventricle", "context": "https://example.org/physiosim/anatomical-contents#heart/lv", "key": "lv_wall", "observed_in_CT": false, "profile": "heart", "relation": "http://purl.obolibrary.org/obo/BFO_0000050", "role": "Wall", "status": "KNOWLEDGE_TEMPLATE_REVIEW", "template_uri": "https://example.org/physiosim/anatomical-contents#heart/lv_wall" } }, { "provenance": { "full_file_sha256": "288cadbe573f8a5488abc135560a66a3c793f48e32984228a7a791cbdcce24da", "path": "experiments/medmlx_anatomy_mapping/results/contents_catalog.json", "pointer": "#/4" }, "record": { "base_id": "UBERON:0000178", "base_iri": "http://purl.obolibrary.org/obo/UBERON_0000178", "base_label": "blood", "context": "https://example.org/physiosim/anatomical-contents#heart/lv_cavity", "key": "lv_blood", "observed_in_CT": false, "profile": "heart", "relation": "http://purl.obolibrary.org/obo/RO_0001025", "role": "Content", "status": "KNOWLEDGE_TEMPLATE_REVIEW", "template_uri": "https://example.org/physiosim/anatomical-contents#heart/lv_blood" } }, { "provenance": { "full_file_sha256": "288cadbe573f8a5488abc135560a66a3c793f48e32984228a7a791cbdcce24da", "path": "experiments/medmlx_anatomy_mapping/results/contents_catalog.json", "pointer": "#/9" }, "record": { "base_id": "UBERON:0002079", "base_iri": "http://purl.obolibrary.org/obo/UBERON_0002079", "base_label": "left cardiac atrium", "context": "https://example.org/physiosim/anatomical-contents#heart/organ", "key": "la", "observed_in_CT": false, "profile": "heart", "relation": "http://purl.obolibrary.org/obo/BFO_0000050", "role": "Structure", "status": "KNOWLEDGE_TEMPLATE_REVIEW", "template_uri": "https://example.org/physiosim/anatomical-contents#heart/la" } }, { "provenance": { "full_file_sha256": "288cadbe573f8a5488abc135560a66a3c793f48e32984228a7a791cbdcce24da", "path": "experiments/medmlx_anatomy_mapping/results/contents_catalog.json", "pointer": "#/10" }, "record": { "base_id": "UBERON:0016513", "base_iri": "http://purl.obolibrary.org/obo/UBERON_0016513", "base_label": "cavity of left atrium", "context": "https://example.org/physiosim/anatomical-contents#heart/la", "key": "la_cavity", "observed_in_CT": false, "profile": "heart", "relation": "http://purl.obolibrary.org/obo/RO_0002572", "role": "Space", "status": "KNOWLEDGE_TEMPLATE_REVIEW", "template_uri": "https://example.org/physiosim/anatomical-contents#heart/la_cavity" } }, { "provenance": { "full_file_sha256": "288cadbe573f8a5488abc135560a66a3c793f48e32984228a7a791cbdcce24da", "path": "experiments/medmlx_anatomy_mapping/results/contents_catalog.json", "pointer": "#/11" }, "record": { "base_id": "UBERON:0000178", "base_iri": "http://purl.obolibrary.org/obo/UBERON_0000178", "base_label": "blood", "context": "https://example.org/physiosim/anatomical-contents#heart/la_cavity", "key": "la_blood", "observed_in_CT": false, "profile": "heart", "relation": "http://purl.obolibrary.org/obo/RO_0001025", "role": "Content", "status": "KNOWLEDGE_TEMPLATE_REVIEW", "template_uri": "https://example.org/physiosim/anatomical-contents#heart/la_blood" } }, { "provenance": { "full_file_sha256": "288cadbe573f8a5488abc135560a66a3c793f48e32984228a7a791cbdcce24da", "path": "experiments/medmlx_anatomy_mapping/results/contents_catalog.json", "pointer": "#/18" }, "record": { "base_id": "UBERON:0006566", "base_iri": "http://purl.obolibrary.org/obo/UBERON_0006566", "base_label": "left ventricle myocardium", "context": "https://example.org/physiosim/anatomical-contents#heart/lv_wall", "key": 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